SARS-COV-2 SPIKE S2-SPECIFIC NEUTRALIZING ANTIBODIES

SARS-CoV-2 spike S2-specific neutralizing antibodies

Since the onset of the coronavirus disease 2019 (COVID-19), numerous neutralizing antibodies (NAbs) against severe Shafts acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed and authorized for emergency use to control the pandemic.Most COVID-19 therapeutic NAbs prevent the S1 subunit of the SARS-CoV-2 spike (S) protein from bi

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A protocol for imaging microvilli biogenesis on the surface of cultured porcine kidney epithelial cell monolayers

Summary: A key facet of epithelial differentiation is the assembly of actin-based protrusions known as microvilli, which amplify apical membrane surface area for various cell functions.To probe mechanisms of microvillus assembly, we developed a protocol using spinning disk Kettle confocal microscopy to directly visualize microvillus biogenesis on t

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Optimizing Emergency Response in Healthcare Facilities: Integration of Firefighting Technologies and Tactical Evacuation Strategies

This study analyzes the implementation of firefighting procedures and evacuation methods in a hospital environment, with a focus on ensuring rapid rescue operations and evacuation methods in a real fire in 2024.This research emphasizes the integration of firefighting technologies, including fire detection systems, real-time communication networks,

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Unsupervised hadronic SUEP at the LHC

Abstract Confining dark sectors with pseudo-conformal dynamics produce SUEPs, or Soft Unclustered Energy Patterns, at colliders: isotropic dark hadrons with soft and democratic energies.We target the experimental nightmare scenario, SUEPs in exotic Higgs decays, where all dark hadrons decay promptly to SM hadrons.First, we identify three promising

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